Dame-Teixeira N. et al. (Eds.) Oral Microbiome: Symbiosis, Dysbiosis and Microbiome Interventions for Maintaining Oral and Systemic Health

Springer, 2025. — 311 p. — ISBN-13 : 978-3031791451Human oral and systemic health exists in a symbiotic relationship with the microbiome. This book explores the dynamics of symbiosis and dysbiosis between the host and the oral microbiome, along with potential treatment strategies that involve modulating the oral microbiome.Systemic inflammatory diseases can communicate through the oral-gut axis, utilizing signals like cytokines and host defensins, which alter gene expression and, in turn, the composition of the oral microbiome. These alterations can lead to oral health issues such as periodontitis and candidiasis. Moreover, conditions associated with metabolic syndrome ― such as obesity, hypertension, hyperglycemia, and dyslipidemia―can worsen oral microbiome dysbiosis. Conversely, the oral microbiota can also affect systemic health.