De S.K. Applied Organic Chemistry: Reaction Mechanisms and Experimental Procedures in Medicinal Chemistry (2 Volume Set)

Weinheim, Germany: Wiley-VCH, 2021. — 806 p. — ISBN 978-3-527-34785-8.The synthesis of natural products, bioactive compounds, pharmaceuticals, and drugs is of fundamental interest in modern organic chemistry. New reagents and reaction methods towards these molecules are being constantly developed. By understanding the mechanisms involved and scope and limitations of each reaction applied, organic chemists can further improve existing reaction protocols and develop novel efficient synthetic routes towards frequently used drugs, such as Aspirin or Penicillin.Volume 1
Rearrangement Reactions
Condensation Reaction
Olefination, Metathesis, and Epoxidation Reactions
Miscellaneous Reactions
Aromatic Electrophilic Substitution Reactions
Pd-Catalyzed C—C Bond-Forming Reactions
Multicomponent Reaction
Volume 2
Oxidations and Reductions
Nomenclature and Application of Heterocyclic Compounds
Synthesis of Some Heterocyclic Compounds Using Named Reactions
Protection and Deprotection of Common Functional Groups
Amino Acids and Peptides
Functional Group Transformation
Synthesis of Some Drug Molecules
Common Laboratory Methods
Common Reagents in Organic Synthesis
Appendix List of Medicines (Partial) and Nutrients