4th edition. — Wolters Kluwer, 2007. — 763 p. — ISBN: 978-0781753425
Now in full color, the Fourth Edition of this text gives students a thorough understanding of microbial agents and the pathophysiology of microbial diseases. The text facilitates learning and recall by emphasizing unifying principles and paradigms, rather than forcing students to memorize isolated facts by rote. Case studies with problem-solving questions give students insight into clinical applications of microbiology. Each chapter ends with review and USMLE-style questions. For this edition, all schematic illustrations have been re-rendered in full color and new illustrations have been added.
PrinciplesEstablishment of infectious diseases
The normal microbiota
Biology of infectious agents
Genetic approaches to studying bacterial pathogenesis
Biological basis for antibacterial action
Innate immunity
Adaptive immunity
The parasite's way of life
Damage by microbial toxins
Infectious AgentsBacteria
Introduction to the pathogenic bacteria
Staphylococci: abscesses and toxin-mediated diseases
Streptococci and enterococci: "strep throat" and beyond
Pneumococcus and bacterial pneumonia
Neisseriae: gonococcus and meningococcus
Bacteroids, intra-abdominal infection, and abscesses
Enteric bacteria: secretory diarrhea
Invasive and tissue-damaging enteric bacterial pathogens: bloody diarrhea and dysentery
Psudomonas aeruginosa: a ubiquitous opportunist
Bordetella and whooping cough
Clostridia: diarrheal disease, tissue infection, botulism, and tetanus
Legionella: parasite of amoebae and macrophages
Helicobacter pylori: pathogenesis of a persistent bacterial infection
Mycobacteria: tuberculosis and leprosy
Syphilis: a disease with a history
Borrelia burgdorferi and lyme disease
Cat scatch disease, bacillary angiomatosis, and other bartonelloses