New York: Springer, 2014. - 290 p.
The “bioelectronic nose”, the device which has a similar function to the human smell sensing system, can be realized by combining the olfactory cells or receptors with nanotechnology. In the last two decades, much has been learned about the smell sensing mechanism in biological systems. With knowledge about the biological olfactory system and the techniques for the expression of biological receptor proteins, we are able to utilize biological materials and systems to mimic the biological olfactory system. In addition to the advances in biological and biotechnological area, nanotechnology has progressed to a great degree. The bioelectronic nose is a good example of the integration of biotechnology and nanotechnology.
The purpose of this book is to provide the reader with a concept, basic sciences, fundamental technologies, applications, and perspectives of the bioelectronic nose.
Concept of Bioelectrouic Nose
Mechanisms of Olfaction
Olfactory Receptor Proteins
Odorant-Receptor Interaction
Cell-Based System for Identification of Olfactory Receptors
Neurobiology and Cultivation of Olfactory Receptor Neurons on a Chip
Production of Olfactory Receptors Using Commercial E. coli Cell-free Systems
Production of Olfactory Receptors and Nanosomes Using Yeast System for Bioelectrouic Nose
Production of Olfactory Receptors and Nanovesicles Using Heterologous Cell Systems for Bioelectronic Nose
Biosensors Based on Odorant Binding Proteins
Optical Methods in Studies of Olfactory System Sang Him Lee, Seung-min Park and Luke P. Lee
Carbon Nanotube-Based Sensor Platform for Bioelectronic Nose
Conducting Polymer Nanomaterial-Based Sensor Platform for Bioelectronic Nose
Applications and Perspectives of Bioelectronic Nose